Vaccine induced erythema nodosum (EN) is well recognized. In this letter, we report a case of a patient who developed recurrent EN following vaccination with the Pfizer-BioNTech BNT162b2 COVID-19 messenger RNA (mRNA) vaccine. Clinicians should be aware that COVID-19 mRNA vaccines can be a possible cause of EN.

Iododerma is an uncommon dermatosis caused by excessive iodine exposure and is associated with significant morbidity and mortality. Because of its heterogenous clinical presentation and variable histopathological findings, which depend on the time the skin biopsy is performed, the diagnosis of iododerma is often delayed. We report a rare case of acute iododerma in a woman with end‐stage diabetic nephropathy with antecedent radioiodine contrast exposure, presenting histopathologically as cryptococcoid neutrophilic dermatosis (CND). We underscore important clinicopathological pitfalls to avoid misdiagnosis with similar overlapping entities such as Sweet syndrome, review all published cases of CND and draw novel insights into its associated entities.