Introduction: The pandemic novel corona virus (SARS-CoV- 2) infects pregnant women and affects pregnancy outcome. The perinatal outcome of COVID positive pregnancies attended at private hospitals during the last epidemic peak at Dhaka is unknown. The purpose of the study was to evaluate perinatal outcome among COVID positive and COVID negative pregnant women who delivered in the 2 study hospitals at Dhaka during the last epidemic wave. Methods: This retrospective study was conducted in 2 eminent private medical college& hospitals in Dhaka,namely Popular medical college &hospital (PMCH) and Greenlife medical college hospital (GLMC) over a period of 3 months from July 2021 to September 2021. COVID positive and COVID negative pregnant women who delivered in the study hospitals during the study period were included in this study. Outcome variables were COVID related maternal morbidity mortality, rate of caesarean delivery, stillbirth, preterm birth, low birth weight, neonatal COVID-19 positivity, neonatal death. Results: This study included 60 COVID positive and 60 COVID negative pregnant cases. COVID positive pregnant women delivered at earlier gestational age (weeks) than COVID negative cases(34.46±3.58 vs 36.50±3.20; p=0.001) Among COVID infected pregnancies,severe disease was observed in 15%; O2 support was needed in 68.3% and ICU admission required in 16.7% cases.The caesarean delivery rate ((93.3% vs 80%; p-.032) and preterm delivery rate (63.3% vs 35%; p-.002) were significantly higher among COVID positive cases. About 8.3% COVID affected pregnancies ended up with stillbirth.Maternal death rate due to COVID related complications was 5%.Proportion of low birth weight (LBW) was significantly more in infected pregnancies (65% vs 35%; p 0.001).No newborn from COVID positive mother was tested positive by RT-PCR at 24 hours of age. Conclusion: SARS-CoV-2 infection during pregnancy cancause moderate to severe disease requiring ICU admission and maternal death in 5% among COVID positive cases .It gives rise to more still birth, preterm birth, increasing number of LUCSand LBW. However maternal to neonatal transmission is not evident at 24-hour RT-PCR testing. J Bangladesh Coll Phys Surg 2022; 40: 270-278

Objective: To compare efficacy and safety of oral misoprostol over vaginal misoprostol for labour induction.Materials and Methods: This is a cross sectional interventional hospital based comparative study which was carried in the department of Obstetrics and Gynecology in DMCH from 01.07.2008 to 31.12.2008.Results: Almost equal number of patients delivered vaginally spontaneously in both group, there is no association between route of administration and mode of delivery. Nausea,vomiting occurred more in oral group and uterine hypertonicity more in vaginal group.Conclusion: In this study, 50 patients were randomly selected for oral group and 50 patients for vaginal group. There were no significant differences regarding age, duration of pregnancy, Bishop's score and indication of induction of labour.KYAMC Journal Vol. 7, No.-1, Jul 2016, Page 668-672

Background: Iron deficiency anaemia is a common problem in antenatal patient especially in primigravida in developing world. The study was conducted to evaluate the efficacy of intravenous iron sucrose in antenatal primigravida anaemic cases. Aims and Objectives: The study was conducted to evaluate the response of intravenous iron therapy in anaemic antenatal primigravida patients. The rise of hemoglobin level was predicted after therapy. Materials and Methods: A prospective cross-sectional study was done in the antenatal clinic of Popular Medical College Hospital from January 2016 to December 2016. Primigravida women of e” 18 years with iron deficiency anaemia were included in this study. Pretreatment hemoglobin level was measured. After total dose of calculated iron, intravenous iron sucrose was infused to achieve the target hemoglobin. After completion of therapy hemoglobin was measured 2 weeks and 4 weeks after last dose of iron treatment. Mean, percentage, Chi-square test was done and P value <0.05 was considered significant. Results: Among the 63 primigravida anaemic patients mean age of the study subjects were 23.98 years with mean gestational age were 23.54 weeks. Their pretreatment hemoglobin level was 5.42 gm/dl. After total dose infusion of iron sucrose, the mean rise of hemoglobin after 2 weeks was 8.87 gm/dl and after 4 weeks was 10.87 gm/dl respectively. This findings were statistically significant (P<0.001). Attainment of target hemoglobin at the range of 9.1-11.0 gm/ dl was 50.79% and 65.08% after 2 weeks and 4 weeks respectively. Conclusion: Parenteral iron therapy in the form of iron sucrose proved to be better choice to correct iron deficiency anaemia in primigravida anaemic patients J Dhaka Medical College, Vol. 27, No.1, April, 2018, Page 79-82

A 33 years old lady presented with history of irregular menstrual cycle followed by menorrhagia. USG revealed left ovarian solid mass but all tumor markers were within normal range. A solid mass on left sided ovary was found on laparotomy. Histopathological examination of the mass showed well differentiated sertoli cell tumor. Tumors of the stroma (Leydig cells) and/or sex cords (Sertoli cells) represent approximately 8% of ovarian tumors and develop from the connective tissue (respectively, interstitial and nurse cells) of the ovary. Because these cells participate in ovarian hormonal function, most of the sex-cord or stromal tumors are able to secrete hormones (estrogens, androgens, corticoids), which explains the hormonal dysfunctions associated with these tumors. Their prognosis are difficult to establish; some of the tumors are almost always benign (Sertoli cell tumors, Leydig cell tumors), whereas others are malignant but with more-or-less delayed local-regional or metastatic relapses.Bangladesh J Obstet Gynaecol, 2016; Vol. 31(1) : 54-56

The occurrence of posterior reversible encephalopathy syndrome (PRES) in patients with eclampsia is a rare condition. PRES is a reversible syndrome characterized by headache, seizure, altered mentation and loss of vision associated with white matter changes on imaging. The lesions in PRES are thought to be due to vasogenic oedema, predominantly in the posterior cerebral hemispheres. This study reports a 32-year-old pregnant woman who presented with headache, dimness of vision, right sided weakness and seizure. The MRI of her brain showed abnormal signal intensity in the white matter of the occipital and parietal lobes. She was treated successfully with pregnancy termination, anti-hypertensives, anticonvulsants, and supportive care. It is concluded that early diagnosis is important to prevent permanent neurologic damage and mortality. Bangladesh J Medicine July 2019; 30(2) : 104-107