The prevalence of radial scar (RS) is 0.04% in asymptomatic women participating in population screening for breast cancer. It is important to differentiate RS from concomitant malignancies, which occur in 20-30% of patients, or from small stellate carcinomas which give similar radiomorphology. The aim of our study was to evaluate the effectivity of current breast diagnostic methods in distinguishing between real RS, concomitant malignancy and carcinomas imitating RS. Diagnosis of RS was set up in 61 cases by mammography. Forty-four patients underwent surgical excision: histology showed benign or malignant lesions in 28 and 16 cases, respectively. A series of negative results at follow-up proved the benign nature of the lesion in further 11 cases. Six patients were not available for follow-up. Results of mammography, physical examination, ultrasonography and cytology were evaluated and were compared in 39 benign and 16 malignant cases. Results of examinations were reported on the BI-RADS scale ranging from 1 to 5. The mean categorical scores of all diagnostic processes were around the level of borderline lesions: mammography: 3.49, ultrasonography: 3.06, cytology: 2.47 and physical examination: 1.67. The average age of the patients in the benign and malignant groups were the same: 58 years. The two groups did not differ significantly over either distribution of coded mammographical results (p = 0.2092), or the distribution of mammographical parenchyma density patterns (p = 0.4875). However, the malignant and benign groups differed significantly from each other over the distribution of coded ultrasonographic (p = 0.0176) and cytological (p < 0.0001) results. In conclusion, in the preoperative diagnosis of asymptomatic "black-stars", mammography detects the non-palpable lesions, and ultrasonography together with cytology proved better in the analysis, provided FNAB is US guided. Due to the complex diagnostic approach the nature of the "black stars" is known in the majority of cases prior to the surgical biopsy.
Briones J, Bordes R et al. PKC-beta 2 protein expression predicts for poor response to chemotherapy and survival in patients with low risk diffuse large B-cell lymphoma. Abstract no. Artiga MJ et al. Building an outcome predictor model for diffuse large B-cell lymphoma. Am. J. Pathol. 2004; 164; 613-622. 6. Schaffel R., Biasoli I, Scheliga A et al. The expression of protein kinase C beta II (PKCb) by immunocytochemistry is predictive of the disease free survival (DFS) in diffuse large B-cell lymphoma (DLBCL). Abstract no.
Absztrakt:
Bevezetés: A tüdősequestratio (TS) sebészi kezelése gold
standard eljárásként alkalmazható. A malignus tüdődaganatok sebészi ellátásában
egyre inkább teret nyerő videothoracoscopos (VATS) technika a benignus
tüdőbetegségek kezelésére is alkalmasnak látszik. Három, radiológiailag
azonosított intralobaris TS VATS műtétjéről számolunk be hazánkban elsőkként.
Módszer: A műtéteket kettőslumenű tubussal megoldott
szeparált lélegeztetéssel, általános narkózisban, a betegek oldalt fekvő
helyzetében két porton (1,5 cm-es kameraport és egy 5-6 cm-es, műanyag gyűrűvel
védett axillaris munkaport) keresztül végeztük. Eredmények,
esetek: A betegek (37 éves nő, 39 és 46 éves férfi) közül kettő
tünetekkel (vérköpés és tüdőgyulladás) a harmadik pedig radiológiai szűrést
követően került kivizsgálásra. A tápláló artéria mindhárom esetben azonosítható
volt a CT képeken. Két esetben jobb alsó, egy esetben bal alsó lebenyt
távolítottunk el nagyobb szövődmény nélkül. Következtetés: A
videothoracoscopos lebeny eltávolítást TS kezelésére is alkalmas eljárásként
ajánljuk.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.