The Quality of Life (QoL) of older adults in nursing homes depends on multiple factors. It is necessary to discover the dimensions of QoL, and to obtain an integrating model, analyzing their relationships. With this aim, an exhaustive systematic literature review has been conducted in this area over the last decade. The research question has been to obtain the advances on the key factors influencing the QoL and well-being of older adults living in nursing homes in the last decade. Multiple databases such as Scopus, Web of Science, Wiley Online Library, PubMed, ProQuest, EBSCOhost, and Emerald were used. This review was reported according to the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) guidelines. “Thematic Synthesis Analysis” was used to analyze the studies. The CADIMA web tool was used to conduct the systematic review. The quality of the studies was assessed. The findings were summarized, obtaining a classification of the relevant studies: models or scales for QoL; vision and perception of the QoL of the stakeholders; and determination of QoL through factors (relationship between factors and predictive factors). The results not only evidence the need for further research into this topic, but also the need for an integrative model of QoL, personalized and adapted both to the residents and the nursing home.
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