In this study, texture feature analysis (TFA) algorithm to automatic recognition of liver disease suggests by utilizing computed tomography (CT), by applying the algorithm computer-aided diagnosis (CAD) of hepatocellular carcinoma (HCC) design. Proposed the performance of each algorithm was to comparison and evaluation. In the HCC image, set up region of analysis (ROA, window size was 40×40 pixels) and by calculating the figures for TFA algorithm of the six parameters (average gray level, average contrast, measure of smoothness, skewness, measure of uniformity, entropy) HCC recognition rate were calculated. As a result, TFA was found to be significant as a measure of HCC recognition rate. Measure of uniformity was the most recognition. Average contrast, measure of smoothness, and skewness were relatively high, and average gray level, entropy showed a relatively low recognition rate of the parameters. In this regard, showed high recognition algorithms (a maximum of 97.14%, a minimum of 82.86%) use the determining HCC imaging lesions and assist early diagnosis of clinic. If this use to therapy, the diagnostic efficiency of clinical early diagnosis better than before. Later, after add the effective and quantitative analysis, criteria research for generalized of disease recognition is needed to be considered.

The purpose of this study were to analyze the clinical correlation between the thyroid autoimmune antibodies (anti-TPO Ab, anti-TG Ab, and TSH) and the maximum standardized uptake value (SUV max ) base on the Hashimoto's thyroiditis and the Graves' disease in diffusely 18 F-FDG uptake of the thyroid gland to the PET/CT image. To achieve this, we was performed the PET/CT examination for the 1,097 subjects from May 2010 to April 2013 in the health screening, and was detected the diffused FDG thyroid uptake, and was additionally performed the thyroid function test (TFT) and the ultrasound (US). As a results, the autoimmune thyroid disease with the diffused FDG thyroid uptake were discovered 39 patients (3.9%), of this, the Hashimoto's thyroiditis was 43.6% and the Graves' disease was 23.1%. Hashimoto's thyroiditis was shown the positive reaction of high titer between the anti-TPO Ab and the anti-TG Ab level, and the correlation coefficient between the SUV max and the anti-TPO Ab was a statistically significant (r>04, p<0.05). Also, Graves' disease was shown the positive reaction of high titer most of the thyroid autoimmune antibodies, and the correlation coefficient between the SUV max and the anti-TPO Ab was a statistically significant (r>05, p<0.01). Therefor, when have a high standard of the SUV max due to the diffusely 18 F-FDG uptake of the thyroid gland, Hashimoto's thyroiditis and Graves' disease were proportionally increased the anti-TPO Ab and TSH level, respectively. The correlation coefficient between the SUV max and the thyroid autoimmune antibodies will be the most influential criterion that was a standard of judgment for the epihpenomenon of the autoimmune thyroid disease, and it will be available for the clinical application.