CKD is commonly found in children with OCRL mutations. CKD progression was strongly related to the underlying diagnosis but did not associate with clinical parameters, such as nephrocalcinosis or proteinuria.
A comparison of drinking in the normal and nephrectomized hooded rat 1,2 Normal ad lib drinking was studied in food deprived nephrectomized, sham operated', and normal rats under the same environmental conditions. Nephrectomized animals drank normal amounts of water until they develo ped obvious symptoms of uremia at about 60 hr.
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