The catalytic application of Cu(INA)2-MOF in click and Biginelli reactions was investigated and a comparative study with the [Cu(INA)2(H2O)4] complex was performed.

No abstract

Herein, we described the synthesis of bis(indolyl)methanes from a Friedel-Crafts reaction alkylation between indoles and aldehydes catalyzed by magnetite Fe3O4 nanoparticles (nano-Fe3O4). The reactions were performed under solvent-free conditions and at room temperature, and the catalyst was recovered magnetically. This greener methodology developed are simple and efficient, affording the desired bis(indolyl)methanes in good yields (40-99 %).