CE credit: For CE credit, you can access the test for this article, as well as additional JNMT CE tests, online at https://www.snmmilearningcenter.org. Complete the test online no later than September 2019. Your online test will be scored immediately. You may make 3 attempts to pass the test and must answer 80% of the questions correctly to receive 1.0 CEH (Continuing Education Hour) credit. SNMMI members will have their CEH credit added to their VOICE transcript automatically; nonmembers will be able to print out a CE certificate upon successfully completing the test. The online test is free to SNMMI members; nonmembers must pay $15.00 by credit card when logging onto the website to take the test.Incidental findings are common in medical imaging. There is a particularly high prevalence of incidental findings within the thorax, the most frequent being pulmonary nodules. Although pulmonary nodules have the potential to be malignant, most are benign, resulting in a high number of false-positive findings. Low-resolution CT images produced for attenuation correction of SPECT images are essentially a by-product of the imaging process. The high number of false-positive incidental findings detected on these attenuation-correction images causes a reporting dilemma. Early detection of cancer can be beneficial, but falsepositive findings and overdiagnosis can be detrimental to the patient. Attenuation-correction CT images are not of diagnostic quality, and further diagnostic tests are usually necessary for a definitive diagnosis to be reached. Given the high number of falsepositive findings, the psychologic effect on the patient should be considered. This review recommends caution when the findings on attenuation-correction CT images are routinely reported. Medi cal imaging uses a range of modalities that yield both anatomic and functional information (1). Visual correlation of images acquired using separate modalities can provide more information than images from a single modality alone, though there is an inevitable risk of misregistration between images that have been acquired during different imaging sessions. The development of hybrid imaging has led to the integration of two modalities in one machine, allowing coregistration of images that have been acquired in a single session (1,2). This allows direct correlation of anatomic and functional information, increasing sensitivity and specificity while adding clarity to indeterminate cases (3). SPECT/CT offers an excellent example of hybrid imaging, combining the functional ability of SPECT with the anatomic ability of CT.The strength of SPECT lies in gaining pathophysiologic detail in a minimally invasive way (4). Pathologic processes can be identified by uptake of radiopharmaceuticals, but the precise location is often difficult to ascertain because of low image resolution and a lack of anatomic landmarks. Moreover, uptake on some scans is often nonspecific, revealing abnormalities but not their specific cause. CT can provide a useful means of localization, also enabl...
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