Amídia, em especial a internet, veicula informações que exploram o corpo da enfermeira como objeto sexual, estigmatizando sua imagem. Alguns fatores contribuem com a definição de um estereótipo negativo à enfermagem: seu passado histórico (por ter sido exercida por mulheres marginalizadas como prostitutas, alcoolistas, analfabetas); a divisão sexual do trabalho; e sua formação fundamentada nos saberes médicos. Concomitante aos relatos históricos, em sites de buscas, digitando-se a palavra enfermeira, encontra-se muitos arquivos estimulantes do imaginário popular que erotizam a profissão, expondo-a a situações constrangedoras. Os arquivos que representam a palavra enfermeiro, entretanto exprimem seriedade. Este artigo reafirma os preconceitos sofridos por uma profissão cuja representação carrega estereótipos assimétricos, e procura apontar estratégias de enfrentamento do problema e divulgação da verdadeira imagem da profissão, revertendo para a enfermagem a notoriedade social que faz jus pela responsabilidade, desempenho e importância de seu trabalho para sociedade global.
The use of drug delivery systems is a good technique to leave the right quantity of medicine in the patient’s body in a suitable dose, because the drug application is delivered directly to the affected region. The current techniques such as HPLC and UV–Vis for the drug delivery calculation has some disadvantages, as the accuracy and the loss of the sample after characterization. With the aim of reducing the amount of material used during the characterization and have a non-destructive test with instantaneous results, the present paper shows the possibility of using electrochemical impedance spectroscopy (EIS) to have a drug delivery measurement during the release phenomena for a calcium phosphate cement (CFC) delivery system with gentamicin sulfate (GS) and lidocaine hydrochloride (LH), at a ratio of 1% and 2%, respectively. The equivalent circuit and the chemical mechanism involved during the measurements have been proposed as a tool to determine the drug delivery profile. The method has been compared with the UV–Vis technique. XRD was realized to verify conditions, before and after release. It was possible to verify the potential for using EIS as an instant technique to quantify drug delivery.
Tricalcium phosphate cement (α-TCP) can be used in various fields of health, including as drug delivery systems. The application of a biomaterial based on α-TCP could enable both the constant drug delivery as support and shape damaged muscleskeletics tissues until which can be regenerated by the organism itself, replacing the biomaterial, while maintaining stable levels of the drug in the organism. The aim of this study was to evaluate the release of gentamicin sulfate using the technique of electrochemical impedance spectroscopy in drug delivery systems of α-TCP. The results obtained in vitro study validated the proposed methodology for assessment of controlled drug delivery systems on the basis of α-TCP.
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