The present review provides a comprehensive insight of pharmacological and therapeutic potential of BCP, its molecular mechanism and signaling pathways in different pathological conditions. The review also examines the possibility of its further development as a novel candidate for various pathologies considering the polypharmacological and multifaceted therapeutic properties potential along with favorable oral bioavailability, lipophilicity and physicochemical properties.

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Carbon monoxide (CO) poisoning is rare in the Arabian Peninsula and occurs almost exclusively during the winter months. Knowledge and perception of the hazards of carbon monoxide is limited. Migrant workers from warm climates appear particularly at risk. We investigated 46 cases of carbon monoxide poisoning presenting at emergency departments from 2007-2009 of the two main hospitals in Al Ain city, United Arab Emirates. Interviews, hospital records, and administered questionnaires were used to collect the data. Among the 46 cases investigated, 24 (52%) were males. Foreign nationals compromised 80% of the cases and the incidence was 3.1 cases per 100,000 residents per year. Burning charcoal in poorly ventilated residences was the predominant source of the carbon monoxide poisoning. Almost all cases (98%) were admitted during the winter months, most in the early morning hours. Carboxyhaemoglobin (COHb) was significantly increased in cases with loss of consciousness and depressed consciousness. There were no reported fatalities.

These are the advance abstracts of the free communications accepted for presentation at the fourth clinical congress of the Gulf Chapter of the American Association of Clinical Endocrinologists to be held on 3 rd -5th of November 2016. One of the main objective of the congress is to give an opportunity to share results of clinical and basic research relating specifically to clinical practice of diabetes care and clinical endocrinology in the region.We present the abstracts of the free communications as submitted by the authors after minimal restyling and editing to suit the publication requirements of the journal. Reflecting mostly the regional epidemiology and clinical practice in diabetes care and endocrinology, were selected for presentations as either oral or poster presentations. By publishing the proceedings of our fourth annual congress in this open access journal, we hope to extend the benefit to those who could not make it to the live presentations and give a safe home for all the abstracts for future reference. Thus making them permanently available to facilitate regional and international networking and collaboration between clinicians and academics of shared interests