We report a case of bilateral regression of choroidal neovascular membrane (CNVM) in a patient following intravitreal Bevacizumab injection. A middle aged myopic patient with fluorescein angiography (FFA) proven bilateral subfoveal CNVM received monthly injections of intravitreal Bevacizumab in one eye. After 3 injections bilateral regression of CNVM was noted in FFA. Possible systemic absorption of intravitreal Bevacizumab resulting in bilateral effect and its clinical implications are highlighted in this case report.