Non-penetrating deep sclerectomy with suprachoroidal drainage ensures the IOP reduction's stability and does not require the use of donor material.

A patient presented to our clinic with stage Ia open-angle glaucoma of the right eye and stage IIa surgically corrected open-angle glaucoma of the left eye. The condition of the ocular surface was interpreted as toxic/allergic conjunctivitis provoked by brimonidine 0.15 %. Brimonidine was substituted with non-selective 0.5%; additionally, topical steroids were prescribed. After steroids were discontinued, some of the symptoms came back, including moderate hyperemia and conjunctival edema, which was interpreted as intolerance to a preservative contained in the eye drops. A decision was made to switch from the β-blocker to its preservative-free formulation; regular IOP monitoring was continued. IOP measured during the next visit was above tolerated, so a preservative-free form of the ocular hypotensive combination drug (an analog of prostaglandin 0.005% with non-selective β-blocker 0.5%) was introduced to the regimen, with further IOP monitoring. Because the initial diagnosis was wrong, damage to the ocular surface had been aggravated by inadequate therapy. Preservative-free hypotensive eye drops are beneficial for the corneal surface and have a positive effect on a patient’s adherence to the regimen.

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Nowadays medicine has great opportunities for a detailed study of organs and systems, quick and accurate diagnosis of norm or pathology. Many diagnostic procedures are universal and are used by doctors of different specialties. Pupillography is a method of studying pupillary reactions, which is based on registering changes in its magnitude by photographing or filming. This study has found wide application in many areas of medicine, such as ophthalmology, neurology, narcology, general medical practice, for the diagnosis of different pathological conditions.Currently, in all areas of medicine, preference is given to objective diagnostic methods. In our country, much attention is paid to the development and introduction into medical practice of new technologies and minimally invasive research methods which purpose is timely accurate diagnosis and effective treatment of various diseases. The visual analyzer transmits visual information to the center of the parasympathetic division of the autonomic nervous system, which is responsible for the work of the sphincter of the pupil and to the center of the sympathetic division, which is responsible for the work of the dilatator. In the pathology of the visual organ, there is a violation of the correctness of information transmission, which can be used for basic research not only in ophthalmology but also in other specialties. Science and technology provides opportunities for ultra-thin, specific diagnostics and monitoring of various physiological and pathological states of organs and systems, the results of which are taken into account in many analyzing programs of the latest devices. Therefore, the importance of studying pupillary reactions is of great interest for many areas of medicine, and more specific studies can improve the accuracy of the diagnosis. This article describes the history of the development of pupillometric and pupillographic methods of research from the middle of the XVIII century and till modern devices. The importance of the study of pupillary reflexes for assessing the state of the visual analyzer and the possibility of using chromatic pupillometry is discussed, the main indicators of the pupillomotor system and their norms are given. Pupillometry provides the ability to accurately quantify changes in pupil size for clinical and research purposes.

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