BACKGROUND: Optimized use of removable dental prosthesis and enhancement of the adaptation period to such orthopedic substituting dental constructions in the oral cavity are the actual aims of practical stomatology. AIM: This study aimed to estimate the psychological state of patients in the process of adaptation to removable dental prostheses and to assess the influence of dental prosthesis fixation on the optimization of adaptation for them. MATERIALS AND METHODS: In the case of psychosensoryanatomicalfunctional maladaptation syndrome, the psychological states of 35 people with partial and 38 with complete tooth loss before and during the adaptation period of their dental rehabilitation for removable acrylic dentures were assessed. The study groups were divided into two subgroups, depending on the method used to improve the fixation of dentures. RESULTS: During the initial examination, all study patients with partial or complete tooth loss had impaired adaptability to these conditions, mainly due to anatomical and functional disorders of the masticatory apparatus. During the adaptation period, an improvement in the psychological status of the patients was noted, especially in those who used the cream for fixation of dentures for domestic production. CONCLUSION: During their adaptation to the removable partial and full dentures, patients are recommended to use the prescribed cream to improve their fixation and thereby allow the reduction of painful symptoms from the prosthetic bed tissues and significantly improve the psychological status of the patients during the adaptation period.

Relevance. Aging of the body leads to the development of an imbalance in the secretory immunity of the oral mucosa, with the loss of natural teeth leading to an even more rapid decline in the host’s oral defense reactions. However, studies on salivary antimicrobial peptides in denture users and their potential role in protecting against the development of inflammation are still scarce at this time.Purpose. To evaluate the effects of full removable acrylic dentures on the oral mucosa and analyze the content of antimicrobial peptides in the saliva of wearers of such dentures.Materials and methods. Sixty-seven (21 men and 46 women) elderly patients (61 to 74 years old) with complete tooth loss were examined and divided into 3 study groups. In the 1st control group the patients did not use any dentures. Patients in groups 2 and 3 were made full removable acrylic dentures for the upper and lower jaws, and in group 2 from the first day of the adaptation period was used domestic denture fixation cream ASEPTA PARODONTAL. Assessment of the denture bed on the hard palate was performed visually using the Schiller – Pisarev test. Microbiological examination for Candida albicans was performed by PCR-diagnostics. The content of antimicrobial peptides in saliva was assessed using ELISA kits by Hycult Biotech.Results. The use of the adhesive cream was found to improve the condition of the palatal mucosa by 25% on the 15th day and by 50% on the 30th day of the adaptation period. Candida albicans was detected in oral material in more than 55% of patients in all groups during their initial examination. In the group of patients using denture fixation cream, a significant decrease in Candida albicans carriage was noted, while an increase in Candida albicans detection of up to 70% was noted in those not using the cream. There was also an increase in the level of cathelicidin LL-37 in the saliva of patients without the use of the cream and with a marked increase in inflammation. One month after dentures in patients without cream use the content of alpha-defensins (HNP 1-3) was significantly lower than that of the group with cream and the control group.Conclusion. On the basis of the carried out clinical and laboratory study, the domestic ACEPTA adhesive cream should be recommended for optimization of the adaptation period to removable acrylic dentures as well as for their permanent use.

Relevance. The majority of elderly and senile patients in the Russian Federation still use removable acrylic dentures, which is associated with the economic problems of the elderly. However, there are few studies devoted to the study of the effect of such dentures on the quality of speech function.   Objective. Evaluation of quality of speech function in the patients with partial and complete tooth loss during the adaptation to the removable dentures including using by patients new home-made adhesive cream for denture fixation.   Materials and methods. Overall 111 (33 male and 78 female) elderly patients with partial (63) and complete (48) tooth loss were examined and were divided into 4 study groups. Groups 1 and 2 included patients with partial tooth loss and groups 3 and 4 included patients with total tooth loss. There were also examined 17 elderly people who had no defects of dentition and formed a control group. The defects of dental rows in the patients of groups 1–4 were eliminated by making removable dentures. At the same time, during the adaptation period, patients in groups 2 and 4 of the study used a new domestic adhesive cream for fixing dentures. Before treatment and during the adaptation period, the quality of speech function of the patients was studied.   Results. It was found that with preservation of the integrity of the dental rows in the elderly people a high quality of speech is observed. Loss of teeth leads to a decrease in the quality of speech function, especially in patients with partial loss of teeth in the anterior part of the jaw or front teeth on both jaws. By the middle of the adaptation period, the quality of speech function had improved in all patients examined, both with partial and total tooth loss. Use of the adhesive cream by patients provided a reliably better quality of speech function with partial and full removable acrylic dentures, which was characterised as «high» at the end of the adaptation period.   Conclusion. On the basis of the conducted research, home-made adhesive cream for denture fixation can be recommended to patients with the purpose of optimization of the adaptation period to removable acrylic dentures as well as for permanent use, which will improve not only fixation and stabilization of dentures, state of the prosthetic bed mucosa, but also the quality of speech function.

Nowadays, each second patient seeking dental care suffers from some pathology of the temporomandibular joint. Most often patients are diagnosed with temporomandibular joint pain dysfunction syndrome, which is poorly treatable and often relapses. Objective: to evaluate changes in the clinical course of TMJ pain dysfunction syndrome when using myogymnastics in the complex rehabilitation of patients suffering from this pathology. Materials and methods. We performed dynamic observation of 62 young patients who suffered from painful dysfunction of the temporomandibular joint, revealed during the preparation of patients for dental prosthetics. Group 1 included 31 people who were treated with the conventional complex treatment to relieve painful dysfunction. Group 2 included 31 people, for the treatment of which the same standard complex of therapeutic and prophylactic measures with the additional application of masticatory muscles myogymnastics was applied. To objectivize the efficiency of using myogymnastics we used the method of severity degree evaluation as well as semi-quantitative method of efficiency evaluation of the treatment of the pathology in question. Results. It was found out that application of masticatory muscles myogymnastics in the complex treatment of painful dysfunction of the temporomandibular joint allows increasing the efficiency of dental rehabilitation of such patients by 6,9% and decreasing the number of patients with recurrence of the disease by 16,1% in the period up to 2 years. Conclusion. As a pathogenetic functional method of treatment of painful temporomandibular joint dysfunction, application of masticatory muscle myogymnastics to patients allowed to develop mutually consistent reflexes of the masticatory muscles, causing movements of the mouth opening (lowering the lower jaw) without its deviation and advancement. It is advisable to include the technique of masticatory muscle myogymnastics for painful TMJ dysfunction in the clinical guidelines.

The prevention of denture stomatitis is an important measure in the clinic of orthopedic dentistry, because at present, in spite of the availability of dentures on artificial supports, full removable dentures are still widely in demand. The study of oral microbiome and mucosal immunity in persons using full removable acrylic dentures was carried out, as it is important for scientifically substantiated development of ways to prevent denture stomatitis. Sixty-seven elderly patients with total tooth loss were examined and divided into 3 study groups. Patients in Group 1 (19 people) did not use any dentures. Patients in group 2 (25 people) had full removable acrylic dentures and from the first day of the adaptation period were offered to use the domestic denture fixation cream Acepta Parodontal. Patients of group 3 (23 people) were also made full removable acrylic dentures, but their adaptation period took place without the use of denture fixation cream. During the clinical-laboratory study it was established that the use of domestic Acepta Parodontal denture fixation cream in patients with full removable acrylic dentures during the adaptation period leads to a decrease in the level of inflammation in the oral cavity, contributes to an increase in mucosal immunity of its mucous membranes, as evidenced by the increased synthesis of secretory immunoglobulin A. At the same time, improvement of oral microbiota was noted, including reduction of detectability of Candida albicans as the main pathogen associated with denture stomatitis.