Background: Usage of information technology is increasing among university students. The extent of usage among medical students is not studied well. The aim of the study is to assess the usage pattern of information technology by first year and second year medical students of government Kilpauk medical college. Chennai. Method: 200 students of first year and second year students were participated in this study. They were interviewed using pretested questionnaire to bring out the different pattern of the internet use and application knowledge of information technology in medical field. Results: Among 200 students 84% of second years and43% of first years access the internet using their mobile phones The application knowledge of information technology (IT) is 97% in second year students when compared to first year student 45%.Majority of students(97%) prefers computer classes to be included in medical curriculum. Conclusion: The usage of information technology by the second year medical students are increasing when compared to the newly admitted students and also the purpose of using IT and knowledge of IT in medical field also improving when they are entering second year.