Objective: Term vaginal delivery after magnetic resonance-guided focused ultrasound therapy (MRgFU) for symptomatic uterine leiomyoma. Study design:A 38-year-old nulligravida underwent MRgFU treatment per study protocol for a solitary 9 Â 10 Â 10 cm uterine myoma and conceived 18 months following the procedure. She was counseled on the unknown implications of MRgFU during subsequent pregnancy. Myoma size increased significantly during gestation. At 39 weeks, she underwent indicated labor induction with vacuum-assisted vaginal delivery of a healthy male infant. Conclusion:In one pregnancy following MRgFU, there were no associated antepartum or intrapartum obstetrical complications.