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Two field trials (2017 and 2018) were conducted at the research field of the University of Education, Winneba, Mampong Campus from May to August to determine the growth and yield response of groundnut to row pattern. The experimental design was a 2 x 4 factorial arranged in a randomized complete block design (RCBD) with three replications. The factors studied included: (A) Cultivar [(i) Yenyawoso and (ii) Adepa] and (B) Row pattern [(i) 50 cm × 10 cm, (ii) 60 cm × 10 cm single row, (iii) 50 cm × 20 cm × 20 cm (iv) 60 cm × 20 cm × 20 cm twin row]. The result revealed that Adepa produced taller plants, higher number of branches at 86 DAP, taller plants, 100 -seed weight and number of pods/ plant than Yenyawoso. The 50 cm × 20 cm × 20 cm twin row pattern produced higher number of branches, taller plants, number of plants harvested and pod yield than other row pattern. The 60 cm × 20 cm × 20 cm twin row pattern produced higher 100 -seed weight and higher number of pods/plant than 50 cm × 10 cm and 60 cm × 10 cm single row pattern. Interaction effect between variety x row pattern was significant with number of branches at 58 and 86 DAP in 2018 cropping season. In conclusion groundnut farmers are to grow Adepa cultivar of groundnut using 50 cm × 20 cm × 20 cm twin row pattern for high yield and vegetative biomass. For heavy seeds farmers should grow Adepa using 60 cm × 20 cm × 20 cm twin row pattern.

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