The effect of natural antioxidants in grade III chemical eye burn was studied in experiments on rabbits at various stages of burn disease. The use of histochrome, Gingko Biloba, and diquertin in combination with complex drug therapy decelerated the decrease in the antioxidant potential of tear fluid and blood plasma. This treatment was also followed by a decrease in the concentration of end products of free radical oxidation.

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Introduction: Choanal atresia is a rare disorder presenting with complete separation between the nasal cavity and the nasopharynx. There are two types of this abnormal blockage of the nasal airway -congenital and acquired. Material and Methods: This paper presents the case of a 54-years-old woman administered to the clinics for septoplasty. During the preoperative diagnostic process via CT scan and endoscope examination a coincidental finding was diagnosed -unilateral congenital choanal atresia. The medical history of the patient revealed difficult nasal breathing which is absent in the right nasal airway, also frequent rhinosinusitis, moreover orthodontic problems with her dentition and malocclusion; regarding her post-birth period she was on feeding tube and with oxygen mask in a neonatal clinic for several months; no facial traumas reported during the rest of her life.Results: Septoplasty was managed and endoscopic assisted fenestration in the choanal regional was performed viatransseptal access. Seven days postoperatively before the removal of the septal splintsa CT scan was performed for evaluation of the surgical treatment and three months later -endoscopy which displayed well-formed without postoperative stenosis neochoana. Conclusion:The congenital choanal atresia is a rare abnormality which determines the insufficient clinical experience with this disorder. It is possible that many cases could have been missed or misdiagnosed because of the low incidence of the condition. The conducted literature review reveals that the case report we are presenting is one of the oldest patients diagnosed with unilateral, congenital, bony choanal atresia.

*Клиника по УНГ-болести при УМБАЛ "Св. Марина"-Варна **Медицински университет-Варна, Факултет по дентална медицина Резюме При реконструкция на тежки септални деформитети за възстановяване на носното дишане се предпочита отстраняването на хрущяла на носната преграда, моделирането му извън носната кухина и връщането му обратно. Екстракорпоралната септопластика представлява радикално решение за "трудните" изкривявания на носната преграда. Целта на настоящата статия е да представи нашия опит при 73 случая с тази техника посредством отворен достъп при 50 пациенти и при 23 чрез ендоназален достъп.