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Adverse drug reactions (ADRs) are associated with clinical morbidity and, in severe cases, even mortality. Globally billions of dollars are spent on managing these ADRs for common and uncommon diseases. The developing world suffers from a high burden of tuberculosis, which requires 6-8 months of multi-drug treatment. In spite of most cases being treatable the problem persists mainly due to a high attrition rate associated with ADR mediated complications. Due to these reasons drug resistant strains have emerged and are now a serious challenge to TB eradication. To effectively deliver the available treatment regimen and ensure patient compliance it is important to manage ADRs more efficiently. Recent studies have demonstrated that drug outcomes are patient-specific and can, therefore be predicted. A few of these drugs, including a few administered for TB, have shown excellent correlation with response rates and development of ADRs. In this review, we profile information available in public domain for existing anti-TB drugs to understand the genesis of ADRs and patient response. Additionally, human genome variation databases have been used to correlate the frequency of these markers and their genomic variants in different populations.

The study was conducted during 2018-2019 to explore the impact of male migration innorth-Bihar in empowering women in different domain of household decisions. Five domainsnamely agricultural production, asset creation, health care, educational decision of childrenand leadership were considered and women empowerment indices were computed for eachdomain. The result revealed that migration of male member adequately empowered only29.44 per cent of women. Larger proportion of women respondents (43.89%) were foundunder moderately empowered category and 29.67 per cent were observed still under lowempowerment group. Women were adequately empowered in studied area to take decisionsrelated to health care, education and agricultural production. The decision to purchase andsale of assets still was under the jurisdiction of male counterpart as the patriarchal systemstill dominated. The role of women in decision making in all the farm activities, fromselection of crops to the sale of farm produce, showed comparatively more moderateempowerment indices. The paper concludes that the women are empowered to varyingextent in situation of male migration from their native places.

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The agricultural pathways to improve the rural year-round access to affordable, diverse, and high-quality foods needs to include all individuals, enterprises, and institutions that influence the supply, demand, consumption, and absorption of food. The interconnected components of a food system lies in diversification of agricultural production system ensuring a level playing field for the production and marketing of nutritious non-staples, such as fresh fruits, legumes, and livestock products and creating a more robust and diversified food system. Bihar had the highest percentage of stunted children among all the states in India. Forty-two percent of children under the age of five in Bihar were stunted, a significantly higher proportion compared to the all-India average of 34.7% and IFS can bring the required diet diversity of household. The Ankuran programme aims to nudge children to eat more nutritious food by creating nutrition and hygiene awareness among students, by setting up poshan vatikas, in schools. Promotion of advanced crop production practices, bio-fortification, Poshan Vatikas, livestock to sustainably improve household availability of nutrition, conserving natural resources and redirecting agricultural policy away from "staple-grain fundamentalism" toward a much broader food systems focus, considering the need to build better connections between agriculture and nutrition.