Purpose: Traditional and complementary medicine has helped discover several medicinally important herbs, understand their mechanism of action and use them as drugs to treat serious medical conditions. In the current review, the role of one such herbal extract, Abelmoschus mochatus (AM) in CNS disorders will be detailed. Approach: Published articles from Pubmed and other sources were used to review and compile the CNS effects of AM.Findings: AM seed extract has shown potent anti-oxidant effects leading to its protective effect in neurological disorders. In addition, it also shows antidepressant, anxiolytic, antiepileptic and sedative properties in animal models. Conclusion: AM can be used as an adjuvant therapy in neurological and psychiatric conditions. Research into the precise mechanisms underlying the CNS effects of Abelmoschus moschatus will aid its use in myriad CNS conditions.