Targeted drug delivery system is a unique type of medication conveyance framework where the pharmacologically dynamic specialists mainly focused on its site activity and not to the non-focused on organs, tissues or cells. Nano sponges are such sort of compelling pharmaceutical transporters, which take care of issues like harmfulness and helpless bioavailability such as they can stack both hydrophilic and hydrophobic medicines. Various classifications of medications can stack into Nano sponge for focused medication conveyance. This targeted drug delivery system is one of the most encouraging methodologies in the existence of science. Nano sponges are little in size with a three-dimensional organization and nanometric depression. Nano sponges are exceptionally permeable and have the extraordinary capacity to ensure dynamic particles and offer programmable delivery. This Review article explains the overall presentation of nano sponges a grouping of nano sponge trademark highlights of nano sponges their points of interest inconveniences, and synthetic compounds utilized in their planning, arrangement of technical factors influencing on the preparation component activities and assessment boundaries with some particular applications.  Keywords: Nano sponges; Targeted drug delivery; Solubility Enhancement; controlled drug delivery.

The present review aims for the study of phytoconstituents and pharmacological activities of some natural plants. The traditional medicinal plants have been found to acquire therapeutic activities significantly antimicrobial, anti-inflammatory antibacterial, anti-fungal, antioxidant properties etc. The plant-derived constituents are majorly for the aliments of used skin disease diabetes, bronchitis, asthma, arthritis, dry cough, ulcer and fever. The antimicrobial activity of the following plants like Justicia adathoda, Lantana Camara, Acacia leucophloea, Holoptelea integrifolia, Calotropis Procera, chlorophytum tuberosum, Bombax ceiba, Bacopa monnieri, Wedelia trilobata, Jatropha gossypifolia were obtained from the extraction of either  leaves, stem or flowers by using ethanol, methanol, aqueous, petroleum ether, chloroform. The phytochemical constituents of the extract have been shown the presence of alkaloids, glycosides, cardiac glucosides tannins, proteins, carbohydrates, saponin, quinines, triterpenes, steroids, polyphenolic, volatile oil, phenols, starch sugar, amino acid, resin and organic acids. This study evidenced the possible use of the mentioned plants as a source of natural medicines which are used as an antimicrobial, anti-inflammatory, anti-bacterial, anti-fungal, antioxidant agents. Keywords:  Medicinal plants, Antimicrobial, Anti-inflammatory, Antioxidants.