The study analysed the profitability of plantain marketing during on and off season in Nsukka local government area of Enugu state, Nigeria. Samples of 60 respondents were randomly selected from four communities within Nsukka Local Government Area to describe the socioeconomic characteristics of plantain marketers, identity the marketing channel of distribution performed, estimate the profitability of plantain marketing in and off season, identify the problems hindering plantain marketing. Data were analysed using, descriptive statistics and cost and return. The result showed that 70% of the respondents were female, within the age bracket of 40-50 years, implying that female of this age range is likely to be more energetic and willing to take risks involved in plantain marketing. Majority of them were married (86.7%) and (60%) have post primary education. Majority (51.7%) of the respondents claim that between January to March is the on-season period with gross margin of N17, 239 while (53.3%) believe off- season is from July-September with gross margin of N23, 775. This shows that it is more profitable to market plantain off- season. Major constraints include seasonality of product, lack of finance, pest and diseases attack, product breakages, lack of market information, price fluctuation and poor access road while cost of transportation, deterioration of product and high market fees are seen as minor constraints. Based on the findings of the study the following  recommendations were made; Storage facilities for plantain should be made available to ensure all year-round production, availability and accessibility of the product.