Lung cancer has been the most common
cancer in the world for several decades. The
non-small cell lung cancer (NSCLC) constitutes
approximately about 80% of the total cases of lung
cancer. Therapeutic interventions in NSCLC have
shifted to the target-based approach from
histology-based approach, and this has completely
changed the face of the management of NSCLC.
Developing countries, such as India, have very
limited data compiled about the prevalence and
treatment practices of lung cancer, despite a
large burden of the disease. However, in recent
times, there has been a lot of data generated in
this regard. This article is an attempt to collate
and shine light on the available data for the
first-line treatment of NSCLC in India keeping in
mind the current standards of care in this
area.
MNTI is a rare dysembryogenic tumor of infancy. It is a benign neoplasm usually seen in the first 6 months of life. The predominant site of origin is the pre-maxilla and the maxilla. It has a rapid expansile growth which manifests with feeding difficulty. The tumor arises from the neural crest cells. Histological examination reveals typical biphasic population of cells with deposits of melanin pigment. Immunohistochemistry (IHC) study helps in confirming the diagnosis. It has a locally aggressive course with high recurrence rate. Malignant transformation and metastatic spread is extremely rare. Wide excision of the tumor is the preferred treatment. Thorough follow-up is recommended for a period of 1 year. Early detection and proper surgery decreases complications with favourable outcome. A case report of this tumor affecting a 5-month old male child with involvement of the right maxillary antrum is being presented here. This case is reported for its rarity, and classical clinico-pathological findings.
Computed tomography (CT) angiography is fast replacing the diagnostic conventional angiography and digital subtraction angiography. A case of a type V portal vein anomaly, which was diagnosed by Doppler ultrasound and confirmed on CT angiography, is presented. Demonstration of the portal vein branching pattern and its anomalies assumed importance and significance after split liver and segmental transplantation techniques were developed. There are 5 variations of portal vein branching that have been described.
Medulloepitheliomas are rare congenital tumours arising from the epithelium lining the medullary tube. They are usually detected in the first decade of life. They may be teratoid or non-teratoid. Regional and distant metastases are rare. Extraocular extension of disease appears to be the most important prognostic feature. Surgical resection is the usual mode of treatment. The role of other adjuvant modalities is as yet unclear.
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