Biological activity of ellagic acid toward some pathogenic strains bacteria (Staphylococcus epidermatis, Bacillus cereus, Klebsiella pneumonia and Salmonella typhi) was studied. The investigation was conducted using plate-agar method. Gentamycin and streptomycin were used as standard drugs. The results show that the biological activity of ellagic acid was more effective than gentamycin and streptomycin.Also, the minimum effective dose of ellagic acid was found to be 0.15 mg|ml, while the minimum effective doses of gentamycin and streptomycin were 0.3 mg|ml and 2 mg|ml, respectively.