BACKGROUND: In this study, the effects of long-term pregabalin use on the choroid and retinal nerve fiber layer were investigated in the fibromyalgia disease. METHODS: The patient group consisted of 41 fibromyalgia patients using pregabalin. The control group consisted of 41 newly diagnosed fibromyalgia patients who had not received any treatment yet. Choroidal and retinal nerve fiber layer thickness measurements were performed with Cirrus HD-OCT (Carl Zeiss Meditec Inc., Dublin, CA, USA) 30 minutes after pupil dilation with 1% tropicamide. RESULTS: There was no difference in subfoveal choroidal thickness, nasal choroidal thickness and temporal choroidal thickness between the patient and control groups (p > 0.05). Increasing the duration of drug use within the patient group was found to thin the retinal nerve fiber layer (p < 0.05). CONCLUSION: We found that pregabalin had no effect on the choroid, while it had a thinning effect for retinal nerve fiber layer. It is recommended not to be preferred pregabalin in fibromyalgia patients with retinal nerve fiber layer damage such as diabetic retinopathy and glaucoma. Patients treated with pregabalin should have regular control in the ophthalmology clinic.

Introduction: Femoral diaphysis fractures are the second most common fractures influencing the lower extremity in children. They occur after high-energy traumas. Surgical treatment has come into prominence over the last 10 years to enhance patient compliance and early mobilization. Objective: We prepared this study to present an example of trauma which may lead to serious permanent disability in pediatric patients and attract attention to the precautions to be taken on this issue. Case: A five (5)-year-old male patient was evaluated in the emergency department with his older brother after a motorcycle accident. The vital signs of the patient with an isolated femoral trauma were found stable. His hemogram and biochemical values were normal. Orthopedic consultation was requested for the patient with an isolated femoral distal diaphysis fracture. He was hospitalized by an orthopedic consultant physician. He was taken into surgery. Fixation was performed surgically with a plate-screw system. The patient was discharged without complications. Conclusion: Since large bone fractures may occur in pediatric patients after a high-energy trauma such as a motorcycle accident, pediatric patients should be legally prohibited from getting on a motorcycle or getting on a motorcycle without protective equipment.