after BNCT. The median duration of the complete response was 24.0 months. The median overall survival time was 32.0 months. Three of the 5 patients are still alive and the remaining patients died of distant metastasis. Open biopsy of the parotid gland was performed in one patient at the selective neck dissection. The pathological examination revealed no residual viable cancer cells in the parotid gland without any serious damage of normal glandular system after BNCT. Although mild alopecia, xerostomia and fatigue were occurred in all patients, no severe adverse effects, Grade 3 and more, were observed in any patients. CONCLUSION: Our preliminary results demonstrate that BNCT is the potential curative therapy for patients with salivary gland carcinomas without causing any serious adverse effects, irrespective of whether the primary site of cancer has already been treated.

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