Background: Urethral stricture patients are often associated with general anxiety disorders. So, our objective was to gather the data of manifestation of anxiety disorder in urethral stricture patients.Methods: We had measured the anxiety level of these patients after two weeks of insertion of catheters (with catheter) and again two weeks after removal of catheter (without catheter) by using the ‘7-item generalized anxiety disorder’ (GAD-7) tool.Results: During the data analysis we have found that amongst the 56 patients included in the study 24 patients had minimal, 12 patients had mild, 11 patients had moderate and 9 patients had severe level of anxiety after 2 weeks of insertion of catheter. Later on, two weeks after removal of catheter 32 patients had minimal, 14 patients had mild, 7 patients had moderate level and 3 patients had severe level of anxiety.Conclusions: So, it can be concluded that urethral stricture disease with an indwelling catheter is an important cause of moderate to severe anxiety and proper intervention plan is crucial for all patients before and after inserting catheter.

Breast cancer is the most common cause of malignancy worldwide in women & second most common cause of death among them. Higher number of cases have been observed from more developed regions than in less developed. In India age adjusted incidence rate of breast cancer is 2.8/100000 than United Kingdom (95/100000).Breast specimens for histopathological evaluation are one of the most common surgical pathology specimens encountered by a surgical pathologist. In regular breast pathology, immunohistochemistry is a useful tool for both diagnostic and prognostic purposes. Although, most breast lesions may be diagnosed using routine hematoxylin and eosin sections; but, in a few situations, such as morphologically equivocal instances or metastatic cancers of unknown source, immunohistochemistry can help to make a more accurate diagnosis.This review will focus on diagnostic immunomarkers. However, the main goal of this review is to assess the diagnostic value of the most commonly investigated immunomarkers in the field of breast pathology by a review of the literature utilising the PubMed (US National Library of Medicine, Bethesda, Maryland) database of indexed publications from 1976 to 2022.