The present study was carried out to evaluate the antiarthritic activity of Glycine max seeds in adjuvant induced arthritis in rats. Antiarthritic activity was assessed based on the paw volume, biochemical parameters, haematological parameters and histological parameters. The changes in the above said parameters were reversed by the G.max seed extract administered at the dose of 60 mg/kg orally. Hence further detailed investigation is required to isolate the compound responsible for the antiarthritic activity