Burn is responsible for an estimated 180,000 deaths annually. A burn is skin damage caused through either high temperature or because of radiation, radioactivity, electricity, or contact with chemicals. A burn is skin damage, which is resulted because of electricity, radiation, radioactivity, or exposure to chemicals. Skin is the primary barrier to infection and burns patients lose their skin the risk of infection persists as the barrier is absent. The leading cause of death after burn injury is sepsis. Sepsis is lethal organ dysfunction caused by a host’s dysregulated response to infection. Multiple antibiotic-resistant bacteria are responsible for the majority of deaths due to sepsis. Third-degree burns go through the skin and deeper tissues are affected. Third-degree burns may need more thorough treatments. Treatment includes intravenous antibiotics to prevent infections, surgical excision, and skin grafting. Treatments given to third-degree burnt patients are not giving satisfactory results. As robotics is a suitable way to work in delicate environments it can be an effective way to deal with sensitive burnt areas. This review focuses on the cause of infection and treatment of burnt patients.