Work-related musculoskeletal disorders (MSDs) are often experienced by welders in the shipyard industry. A study was conducted in one of the shipyards in Malaysia to identify the prevalence of work-related MSDs among welders and the factors attributed to its increase in the workplace. The investigation was carried out using a modified Nordic questionnaire, in which 27 shipyard welders were interviewed. The questions ranged from demographic information to the prevalence of MSDs on parts of body region experiencing discomfort and pain. The results showed that the most affected body regions were neck, upper back, and lower back, which comprised of 74.1%, 70.4%, and 63.0%, respectively, of the respondents being interviewed. A further in-depth study was conducted for the three most affected body regions with respect to work activities such as working posture, repetitive work, and lifting of heavy objects during welding. The frequency of prevalence of work-related MSDs on these body regions experienced by the welders showed that 25.9% of the respondents had frequently encountered neck pain and another 11.1% of them sometimes experienced discomfort while performing repetitive actions. The study also showed that 22.2% of the respondents sometimes experienced shoulder pain whereas 3.7% of them had reported to seldom encountered it when performing welding operation in awkward positions. Almost half of the respondents (i.e., 48.50%) experienced discomfort and pain for both elbow/hand and wrist when lifting objects heavier than 5 kg.