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Introduction: Ischemic heart disease (IHD) is one of the leading causes ofdeath. Short sleep duration may increase the risk of coronary artery disease (CAD). The studywas designed to evaluate the association between CAD and sleep duration. Objectives: Todetermine the frequency of patients who have short sleep duration may suffer from CAD. Studydesign: Case series. Setting: Punjab Institute of Cardiology (PIC), Lahore. Period: It was carriedout in six months. Methods: 400 patients admitted who presented with IHD. Sleep durationwas categorized into three categories like <6 hours, 6-8 hours and >8 hours. Angiographywas performed for patients who have CAD. Results: Sleep duration was <6 hours, 6–8 hours,and >8 hours in 172 (43%), 124 (31%) and 104 (26%) patients respectively. Significant CADwas presented among 84 (21%) patients of sleep duration <6 hours, 16 (4%) patients of sleepduration 6–8 hours and 32 (8%) patients of >8 hours sleep duration. Conclusions: Significantnumber of patients has short sleep time and suffering from CAD.