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We have investigated the frequencies of sister chromatid exchange (SCE) induced by pulse-wave ultrasound in lymphocytes obtained from the human umbilical vein. The following results were obtained : 1) There is an increase in the frequency of SCEs with increases in acoustic power. 2) The critical acoustic power was 37.3-73 mW/cm2 (spatial average temporal average, SATA). 3) Regardless of changes in pulse duration and repeated pulse frequency, if the acoustic power remains constant, the SCE frequency does not change significantly.sister chromatid exchange ; ultrasound ; human lymphocytes ; acoustic power ; pulse-wave ultrasound

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