A case of a term female newborn, 40-week gestational age (by ultrasound (US)) with prenatal diagnosis of situs inversus and levocardia is reported. Transposition of the great arteries (TGA) and irregular fetal bradycardia were prenatally detected. Immediately after birth, electrocardiogram (ECG) monitoring revealed a complete heart block with no sign of hemodynamic compromise. The patient was then transferred to the neonatal intensive care unit (NICU) for ventilatory support. Close observation and further investigation with echocardiogram were undertaken. The patient was transferred by air at the age of 4 days to the Queen Sirikit National Institute of Child Health for definitive cardiovascular treatments. This paper describes how to overcome the challenges of transporting a very young neonate with complex cardiac problems.