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Synthesis and Innate Immunosuppressive Effect of 1,2-Cyclopentanediol Derivatives. -1,2-Cyclopentanediol derivative (VIII) and a series of structurally related compounds, e.g. (IX), are synthesized and evaluated for their immunosuppressive activity. Compared to the primary lead (VIII), several methylamide-or arylamide-containing analogues like (IX) are 20-25 times more potent. -(KIKUCHI*, H.; OKAZAKI, K.; SEKIYA, M.; URYU, Y.; UEDA, K.; KATOU, Y.; KURATA, S.; OSHIMA, Y.; Eur.