The findings suggest the value of a methodical assessment when developing a systematic plan for implementing an institutional culture of evidence-based practice.

:Sepsis identification and treatment has changed significantly over the last few decades. Despite this, sepsis is still associated with significant morbidity and mortality. This first of a two-part series reviews the history of modern sepsis and presents new research in pathophysiology, treatment, and postsepsis care.

The Surviving Sepsis Campaign 2012 Guidelines offer recommendations for the care of severely septic patients. These guidelines are appraised and summarized briefly in this article, and a case example illustrates the integration process. These guidelines are important for multidisciplinary team members working together toward the common goal of reducing sepsis mortality.

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