We report a 2.21-Mbp draft whole-genome sequence of Lactobacillus fermentum Qi6 (LfQi6). This strain demonstrates activity against pathogenic biofilms, enhances the skin barrier, and upregulates innate immune defenses. The genome sequence information of this strain will help to identify molecules that hold promise for the discovery of novel therapeutics for dermatological disorders.

No abstract

Heterozygous mutations in Factor V Leiden (FVL) or prothrombin G20210A (PT-G20210A) are relatively common; the presence of double-heterozygosity for these mutations is rare but may be as high as 5% in patients with deep vein thrombosis (DVT). Antiphospholipid syndrome (APS) is a rare autoimmune disorder and commonly presents in adolescents and young adults. This report describes the diagnosis, treatment, and outcome for acute presentation of extensive lower extremity DVT and saddle pulmonary embolism (PE) in a previously healthy 17-year-old male found to have multiple genetic risk factors including double-heterozygosity for FVL/PT-G20210A and concurrent APS, which is rare and not well-described.