Systemic Lupus Erythmatosis (SLE)is an autoimmune disease that can affect all organ systems. The natural history of the cardiovascular manifestations has been altered by systemic corticosteroids used for treatment of SLE. Thus, young patients with SLE may suffer from angina and myocardial infarction. We report our experience of coronary artery bypass grafting in a case of SLE. In this case vessels were diffusely diseased so we did patch angioplasty in these vessels. In conclusion, although the postoperative complications are common, coronary artery bypass grafting could be performed in patients with SLE. Severity of disease, use of appropriate graft and their long term results are the areas which needs extensive research. (Ind J Thorac Cardiovasc Surg 2009; 25: 27-28)
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