Nimotuzumab is an anti group of anti-epidermal growth factor receptor the EGF protein receptor, such as colorectal, brain, pancrea cervical and breast cancer. In order to obtain a of the above-mentioned cancers, nimotuzumab and gamma-emitter 177 Lu. This report discuss vivo tests, which included cytotoxicity, clearance, imaging and biodistribution tests. The cytotoxicity test of (lung carcinoma) was found unradiolabeled nimotuzumab. The on normal rats showed that the residue the urine. The biodistribution and image tests showed that 177 Lu-DOTA-nimotuzumab there organs, such as the kidney, liver and bone post injection of 177 Lu-DOTA nearly the same as or slightly lower compared to other radiolabeled monoclonal antibodies, precautions still ha tested on cancer patients.
Abstract:The Sidoarjo mudflow in East Java, Indonesia, has been erupting since May 29 th , 2006. The eruption has been known as the Lusi (lumpur Sidoarjo), which was previously considered as a remote seismic event consequence, but current geyser-like activities show an association with a geothermal phenomenon. A method of characterizing rare earth elements (REE) is commonly an effective tool for recognizing a geothermal system, and here it is adapted to particularly indicate the environmental origin of the Lusi mud. Results show that the Lusi hot mud is made of a porous smectite structure of a shale rock type, which becomes an ideal tank for trapping the REE, especially the light REE. Volcanic activities seem to be an important influence in the eruption; however, since there is a lack of significant isotopic evidences in the mobilization of the REE during the eruption, the chloride neutral pH water of the Lusi may hardly contain the REE. The moderate Ce and Eu anomalies found in the REE patterns of the mud strongly indicate a sea-floor basin as the most probable environment for the REE fractionation during the sedimentary rock formation, in which the weathering processes of volcanic rock origin enriched the Lusi shale with the REE.
Penelitian ini menggunakan penelitian tindakan (action research) sebanyak tiga putaran. Setiap putaran terdiri dari empat tahap yaitu: rancangan, kegiatan dan pengamatan, refleksi, dan refisi. Sasaran penelitian ini adalah siswa Kelas II SD Negeri 3 Depok Kecamatan Bendungan Kabupaten Trenggalek semester I Tahun pelajaran 2012/2013. Dari hasil analis didapatkan bahwa metode diskusi memiliki dampak positif dalam meningkatkan prestasi belajar siswa.hal ini dapat dilihat dari semakin mantapnya pemahaman siswa terhadap materi yang disampaikan guru (ketuntasan belajar meningkat dari sklus I, II, dan III) yaitu masing-masing 64,00%, 80,00%, dan 88,00%. Kesimpulan dari penelitian ini adalah metode Diskusi mempunyai pengaruh positif, yaitu dapat meningkatkan motivasi belajar siswa.
This research aimed to determine the promotional strategy and sales increase at CV. Jaya Perkasa Motor Rancaekek Kabupaten Bandung. The method used in this research was quantitative method with descriptive verification approach, that is the research method used to describe the facts or circumstances at the time the research took place and to test the truth of the hypothesis then concluded. Analysis results shows that the determinant coefficient (R2 ) between variables X and variable Y is R2 = 0,469 meaning that the contribution of X to Y is 46,9% and the remaining 53,1% is influenced by other factors not examined in this research, so the level of the relationship between determination of promotional strategy and sales increase is said to be good enough. The suggestion for the company must carry out adjustment in promotional improvements that are set to get the expected benefits and the company must be able to be more creative and innovative in carrying out all promotional strategy.
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