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Background-Evidence suggests that long-term trajectories of depressive symptoms vary greatly throughout the population, with some individuals experiencing few or no symptoms, some experiencing transient symptoms and others experiencing chronic depression. The goal of this paper was to review studies that examined heterogeneity in long-term trajectories of depressive symptoms and summarize the current knowledge regarding a) the number and patterns of trajectories and b) antecedents and outcomes associated with different trajectory patterns.

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