Background: Premature infants have avascular or incompletely vascularized retina at birth and ROP evolves over 4-5 weeks after birth. The aim of this study is to know the prevalence of retinopathy of prematurity in preterm infants, with birth weight ≤ 1500 grams and/or gestational age ≤32 weeks in a tertiary care center.Methods: The study was conducted in Kovai Medical Centre and Hospital Coimbatore in 2016. The sample size is 95 babies. All preterm infants admitted with a birth weight of ≤1500 grams and/or ≤ 32 weeks of gestation and baby those at risk of ROP.Results: 95 babies have enrolled during the study period of which 78 babies fulfilled the inclusion criteria and completed this prospective study.12 babies could not complete the follow-up protocol and 5 babies died before full vascularization of the retina. 78 babies who fulfilled the inclusion criteria were screened and 15 babies were found to have ROP. The prevalence of ROP in this study is 19.2%.Conclusions: Among the preventable causes of blindness in children, ROP figures very high on the agenda. Low birth weight and gestational age were found to be the most important risk factors for the development of ROP.

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This paper describes a typical patient with congenital adrenogenital syndrome who conceived following cortisone treatment and was delivered recently of a normal female infant by caesarean section. In this particular patient the signs of virilisatwn became manifested as late as 14 years. As far as we are aware, this is perhaps the first paper where serial steroidal analyses during prenatal and lactational amenorrhoea lasting up to eight months are reported.

Necrotising fasciitis is rapidly progressive inflammation with infection and secondary necrosis. The incidence of it is increasing recent times. The challenge associated with its treatment is identification of the process at an earlier stage to improve outcome and reduce the dreadful complications. To study the socio-demographic, clinical, microbiological, risk factor profile and complications of patients diagnosed with necrotizing fasciitis. It was a cross sectional descriptive study carried out in surgery ward of a tertiary care teaching hospital. Patients diagnosed with necrotising fasciitis were included in the study. After detailed clinical and laboratory evaluation appropriate surgical and medical interventions were administered and were followed to note the outcome. Epi Info software version 3.5.3 was used for data entry and statistical analysis. 82% of the study participants were more than 40 years old and 76% of them were males. All of them had fever, pain and tenderness, 76% of them had swelling and 50% of them had foul smelling discharge. The commonest site involved was lower extremity (36%). Diabetes mellitus as a predisposing factor was found in 52%. 84% of the infections were polymicrobial and E. coli was isolated from 74% among them. 34 % had developed complications during hospital stay. Though it is a dreadful infectious condition prompt recognition decreases morbidity and mortality. The risk factors identified, complications occurred needs to be given importance to improve treatment outcome among patients admitted with necrotising fasciitis.