Sleep-disordered breathing (SDB) describes a number of disorders, characterized by partial or complete cessation of breathing during sleep, with obstructive sleep apnea (OSA) being the most common form of SDB. SDB prevalence is increasing over the last decades because of increasing prevalence of obesity, improvement in diagnostic methods, and aging of the population. 1 The prevalence of moderate to severe SDB (defined as apnea-hypopnea index ≥ 15/h of sleep) in Belgium is estimated to be 15.7%. 2 Different studies have shown a strong link between the presence of SDB and cardiovascular morbidity and mortality. 3,4 Lung transplantation (LTX) is an effective and important treatment option for selected patients with a variety of end-stage
The incidence of clinical PJP in patients treated for metastatic cancer is substantial. A high index of suspicion, especially in cases with unexplained respiratory symptoms, concurrent or recent use of steroids, a normal CXR and otherwise unexplained increased lactate dehydrogenase levels, is critical. The threshold for performing a CT-scan must be low and the diagnosis needs to be confirmed microbiologically.
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