Importance: Previous research has calculated normative data for the Dynavision D2 Visuomotor Training (D2) System among healthy athletes to understand concussion management, but to date no studies have identified the norms for healthy adults over a large age range (18-80 yr) for physical response speed. Objective: To provide normative data for the D2 for physical response speed in adults ages 18-80 yr. Design: Cross-sectional, descriptive study to obtain normative data on physical response speed using the D2 for adults in age categories 18-40, 41-60, and 61-80 yr. Setting: Genesis Physical Therapy and Wellness Center, a Midwestern outpatient hospital-based therapy center. Participants: Three hundred adults, stratified into three different age categories. Normal standards with quartiles were identified for each age and sex category. Outcomes and Measures: Multiple regression model of the inverse response times. Results: The results showed a significant difference in physical response speed between men and women and between the different age groups. Women in all age categories were slower than men. Physical response speed increased with age in both sexes, but each had significantly different age and sex main effects (p < .0005). Conclusions and Relevance: Occupational therapy practitioners can use the normative standards identified in this study in their assessment of clients with visual and cognitive deficits after a brain injury, stroke, or other neurologic pathology. What This Article Adds: This study's results can be added to the battery of other common evaluation measures that occupational therapists use to evaluate visual and cognitive deficits after neurological impairments.