Functional constipation is a common bowel disorder in the communitywhich affects one in six children. The overall prevalence of constipation was 14.7%and 4.6% for FC while only 1.8% of respondents reported laxative use every day.The aim of this study is to evaluate the current trend of diagnosing and treatment of functional constipation among children. After getting informed consent, we reviewed the prescription of these patients, and data was collected using a semi-structured pre-validated questionnaire. Data were entered in Microsoft excel 2010 and statistical analyses were done using SPSS 17. The total number of cases included in the study was 138. Of which majority of cases are in the age group of below 5 years with a female preponderance. Almost all the cases reported laxatives use for the relief of constipation along with few dietary modifications. Lactulose and PEG played a major role in FC.Dietary habits and physical activity also played an important role as FC children reported low fruit and vegetable consumption, high fast-food consumption, and low levels of physical activity.

COVID-19 is currently well known among the general population. The current pandemic treatment requires patient compliant, safe, tolerable, and orally effective. RNA dependent RNA polymerase (RdRp) is an important enzyme involved in RNA synthesis by the formation of phosphodiester bonds within the virus. Effective oral antiviral agents are urgently needed to treat, block transmission and prevent progression to severe illness in COVID-19. Molnupiravir is a orally active RdRp inhibitor. The Developmental steps of molnupiravir includes prophylactic efcacy in a ferret model and its therapeutic efcacy against COVID-19 patients has been proven.

To report case presentations of cervical myelopathy with ossication of the posterior longitudinal ligament (OPLL) due to uorosis. Fluorosis is regularly found in a particular place or among a particular group of people which always goes unnoticed unless otherwise, complication develops. It may be prevented easily if you identify and treat it promptly. The skeletal system is one of the supporting systems of our body that gets affected by uorosis and leads to catastrophic changes. So, it is always necessary to monitor the people living in an endemic area and also people presenting outpatient departments with spine problems.