Kazem Mahmoud scite author profile

In the present work, we succeeded to synthesize the novel indolo‐spirocyclic compounds (4, 5, 6, 7 and 11) via electrophilic condensation reactions of indoles with carbonyl compounds including different types of ketones, for example, heteroacetyl ketones (3‐acetylindole and 3‐acetylpyridine), cyclohexanone, isatin, cyclohexane‐1,4‐dione, whereas an attempt to prepare the spirocyclic 9 failed. This new idea will open a high prospective for continuous investigations related to the synthesis of novel indolo‐spirocyclic compounds.

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Multitargeted drug development: Discovery and profiling of dihydroxy substituted 1-aza-9-oxafluorenes as lead compounds targeting Alzheimer disease relevant kinases

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Holzer

Herrmann

et al. 2012

Bioorganic & Medicinal Chemistry Letters

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Kazem Mahmoud

Discovery of 4-anilino α-carbolines as novel Brk inhibitors

Synthesis of β-Nitroamines via Classical Mannich and Aza-Henry Reactions

Synthesis, cytostatic evaluation and structure activity relationships of novel bis-indolylmethanes and their corresponding tetrahydroindolocarbazoles

Synthesis of Novel Indolo‐Spirocyclic Compounds

Multitargeted drug development: Discovery and profiling of dihydroxy substituted 1-aza-9-oxafluorenes as lead compounds targeting Alzheimer disease relevant kinases

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Kazem Mahmoud

Discovery of 4-anilino α-carbolines as novel Brk inhibitors

Synthesis of &#946;-Nitroamines via Classical Mannich and Aza-Henry Reactions

Synthesis, cytostatic evaluation and structure activity relationships of novel bis-indolylmethanes and their corresponding tetrahydroindolocarbazoles

Synthesis of Novel Indolo‐Spirocyclic Compounds

Multitargeted drug development: Discovery and profiling of dihydroxy substituted 1-aza-9-oxafluorenes as lead compounds targeting Alzheimer disease relevant kinases

Contact Info

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Synthesis of β-Nitroamines via Classical Mannich and Aza-Henry Reactions