Objective Identify drug information (DI) resources used in neonatal practice guidelines in low‐ and middle‐income countries. Methods Individuals with knowledge of national neonatal guideline development completed a descriptive, cross‐sectional survey. Key findings Eighty‐five per cent (33/39) of respondents fully completed the survey. Physicians from university hospitals in Africa were primary respondents. Forty‐five per cent (15/33) used a single national neonatal guideline. Primary neonatal resources for drug dosing and preparation were as follows: (1) World Health Organization Pocketbook of Hospital Care for Children, (2) Pediatric & Neonatal Dosage Handbook and (3) National Institute for Health and Care Excellence for Infants and Neonatal pathways. Conclusion Low‐ and middle‐income countries with single national neonatal guidelines cite a finite range of DI resources.