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A 40-year-old-woman presented with swelling and pain of the right buccal mucosa. The swelling protruded intraorally. An incisional biopsy revealed pleomorphic adenoma in the pterygomandibular space. The tumor was surgically removed via a mandibular swing approach. The entire resected specimen was submitted to histopathological evaluation, which showed solid and myxomatous areas, typical of pleomorphic adenoma, throughout the tumor specimen. No recurrence was observed during 3 years of follow up.