Tetramic acid derivatives are an important class of nitrogen heterocycles with a pyrrolidine-2,4-dione core as a key structural motif. From the sponge-derived fungus Beauveria bassiana, a new equisetin-like tetramic acid derivative, beauversetin (1), was isolated. The sea weed-derived fungus Microdiplodia sp. produced the tetramic acid derivative 2 (Sch210972) which was shown to inhibit human leucocyte elastase (HLE) with an IC 50 of 1.04 µg mL-1 .

Chemical investigation of the fungus Trichoderma sp., isolated from the Caribbean sponge Agelas dispar led to four novel sorbicillinoid polyketide derivatives (1–4) with an unprecedented tricyclic ring system. The structures of all compounds, including the absolute configuration, were determined by interpretation of their spectroscopic data (1D and 2D NMR, CD, MS, UV and IR), and molecular modeling calculations. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2007)

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Die Entfernungsabhangigkeit von Anziehungskriiften zwischen zwei Korpern bestimmte Anitu Eaifey (London, England), Zwei Glimmerplatten wurden an einer Kante fest miteinander verbunden iind an der gegeniiberliegenden Kante durch einen zwischen sie gelegten Glasstab gespreizt. Bei Fehlen von Anziehungskraften zwischen beiden Platten ergibt sich die Form der gebogenen Platten aus der Elastizitatstheorie. Die