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A 32-year-old woman presented to Kasturba Hospital, Manipal with the features of gastroenteritis and one episode of generalised tonic clonic seizure with loss of consciousness for 5 min. No abnormalities were found during neurological examination. Her baseline investigations showed low sodium, low serum osmolality, normal renal and liver function tests, urine myoglobin and antinuclear antibodies profile were negative. Incidentally her creatine kinase (CK) levels were found to be very high. She was treated with intravenous fluids and high salt diet for hyponatraemia. With correction of hyponatraemia, CK levels also improved, suggesting the probable diagnosis of hyponatraemia induced myopathy leading to hyperCKaemia. The importance of early recognition of this potentially-dangerous and rare condition is emphasised.

AIMTo evaluate the role of dietary supplementation of Omega-3 fatty acid in treatment of dry eye associated with meibomitis. MATERIAL AND METHODA prospective, interventional study was done at HIMS, Varanasi. Hundred eyes of fifty patients were studied for changes in dry eye status after starting 500 mg of Omega-3 fatty acid [Eicosapentaenoic Acid 325 mg and Docosahexaenoic Acid 175 mg] twice a day for three months. There were four patient visit (at baseline, 1 month, 2 month, and 3 month). On each visit recording of corrected distance visual acuity, slit lamp examination, questionnaire base symptom evaluation and scoring was done. Objective evaluation was done by Schirmer 1 test, Tear Film Break-Up Time (TBUT). RESULTA total of fifty patients participated in the study of which 35 patients were female and 15 were male. All the patients were in the age group 45 years-75 years mean being 60.0±5.5 years. At last visit, 60% of symptomatic patients were asymptomatic and 40% had moderate improvement in symptom score. >90% patient showed significant improvement in Schirmer test values by 3-month follow-up. On evaluating TBUT, nearly 80% patients had scores within normal range by the end of the study. CONCLUSIONRecent advances in understanding the pathophysiology of DES has led to evolution of newer modalities of treatment. Omega-3 fatty acid modulate the inflammatory process in the body may have a promising role to play in dry eye.