An indoor feeding experiment for 57 days was conducted on Nile tilapia to evaluate the effects of dietary inclusion of graded levels (0, 50, 75, and 100%) of sieving wastes meal of Egyptian clover seeds instead of soybean meal based on crude protein content. A total of 8 glass aquaria (each of 70 × 35 × 40 cm, filled with 65 L dechlorinated tap water, and stocked with 12 fingerlings 17.3 g as average initial body weight and 9.5cm as average total length) were used. The obtained results recommended the best replacement level of 50% which significantly realized the best feed composition, highest feed consumption, final body weight, and best body composition of Nile tilapia, to be reflected in many benefits for both the producers and the consumers.