A three-component reaction between trialkyl phosphites, dialkyl acetylenedicarboxylates and 4-hydroxycoumarin is described as a simple and efficient route for the synthesis of 3-[2-(dialkoxyphosphoryl)-1,2-dialkoxycarbonyl-ethyl]-4-hydroxycoumarins in high yields.
Organo-phosphorus compounds S 0080 Stereoselective Synthesis of 3-[2-(Dialkoxyphosphoryl)-1,2-dialkoxycarbonyl-ethyl]-4-hydroxycoumarins by Reaction Between Trialkyl Phosphites, Dialkyl Acetylenedicarboxylates and 4-Hydroxycoumarin. -(ANARY-ABBASINEJAD*, M.; CHARKHATI, K.; HASSANABADI, A.; J. Chem. Res. 2009, 5, 319-321; Dep. Chem., Islamic Azad Univ., Yazd, Iran; Eng.) -H. Toeppel 44-175
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