Single parenteral administration of ketorolac tromethamine produced a lymphotropic effect, which was manifested in acceleration of lymph flow in the thoracic duct and increase in contractile activity of the wall and valves in mesenteric lymphatic microvessels of rats with fever. These changes improved lymph circulation.
Single injection of mexidol (drug with antioxidant and membranotropic effects) to animals with reactive fever produces a multicomponent effect on the lymph circulation. The drug increased the number of functioning lymph capillaries and contractile activity of wall and valvular leaflets in rat small intestinal mesenteric lymphangion, accelerated lymph drainage, thus stimulating lymph formation and lymph flow.
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